Clinical review 79: Angiotensin II: an insulin-sensitizing vasoactive hormone?
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چکیده
منابع مشابه
Angiotensin II: a vasoactive hormone with ever-increasing biological roles.
Angiotensin II (Ang II) is an octapeptide hormone that plays a central role in cardiovascular homeostasis. Typical of many proteins, Ang II was named on the basis of its first-demonstrated biological function—the ability to act as a vasoactive agonist and induce contraction of blood vessels. Over the years, Ang II has been shown to play important roles in mediating hypertension, heart failure, ...
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Adiponectin, an adipose-specific secretory protein, exhibits antidiabetic and antiatherogenic properties. In the present study, we examined the effects of sex hormones on the regulation of adiponectin production. Plasma adiponectin concentrations were significantly lower in 442 men (age, 52.6 +/- 11.9 years [mean +/- SD]) than in 137 women (53.2 +/- 12.0 years) but not different between pre- an...
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Atypical endometrial hyperplasia has been associated with progression to endometrial cancer, the most common genital malignancy. There are multiple risk factors for endometrial cancer, such as early menarche, exogenous estrogen exposure, obesity and diabetes. Diabetics have a 3-4 fold relative risk of endometrial cancer. Also, several studies have demonstrated an association between insulin res...
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Porcine /3-melanocyte-stimulating hormone and angiotensin II were examixied as acceptors in the reaction catalyzed by arginyl-tRNA-protein transferase. Both inhibited enzymatic transfer of [l%]arginine from tRNA to bovine albumin. Inhibition was competitive with albumin and the Ki values were, respectively, 15 and 0.8 PM. The expected arginylated compounds were isolated and characterized. &Mela...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1996
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.81.4.8636320